Cutaneous Melanoma Classification: The Importance of High-Throughput Genomic Technologies

Cutaneous melanoma is an aggressive tumor responsible for 90% of mortality related to skin cancer. In the recent years, discovery driving mutations in has led better treatment approaches. The last decade seen a genomic revolution field Such production unprecedented mole data. High-throughput technologies have facilitated genomic, transcriptomic and epigenomic profiling several cancers, including melanoma. Nevertheless, there are number newer that not yet been employed large studies. this article we describe current classification cutaneous melanoma, review knowledge main genetic alterations their impact on targeted therapies, most high-throughput technologies, highlighting advantages disadvantages. We hope will also help scientists identify suitable technology address melanoma-related relevant questions. translation all actual advancements into clinical practice be helpful defining different molecular subsets patients provide new tools questions disease management. Genomic might indeed allow predict biological - and, subsequently, behavior each subset as well even changes cell populations during evolution toward real achievement personalized medicine.